Simultaneous Quantification of Some Fluoroquinolone Residues in Real Wastewater Effluents Using CZE

Since active pharmaceutical ingredients (APIs) are directly related to human health, monitoring and quantifying them in the environment is a crucial challenging issue. Using capillary-zone electrophoresis (CZE), four frequently used fluoroquinolones (FQs), ciprofloxacin, sparfloxacin, moxifloxacin, gatifloxacin, were efficiently isolated measured industrial wastewater. Solid-phase extraction (SPE) was developed as an efficient sample pretreatment procedure. The capillary electrophoretic procedure’s various parameters tuned produce optimal separation pattern for drugs under consideration. All of study quantified concentration range 0.5 50 µg/mL. After full assay validation compliance with ICH-Q2B criteria, real wastewater samples subjected effective SPE, proposed successfully determine examined FQs samples.